LMP2

Epstein-Barr virus (EBV) latent membrane protein 2 (LMP2) are two viral proteins of the Epstein–Barr virus. LMP2A/LMP2B are transmembrane proteins that act to block tyrosine kinase signaling. LMP2A is a transmembrane protein that inhibits normal B-cell signal transduction by mimicking an activated B-cell receptor (BCR). The N-terminus domain of LMP2A is tyrosine phosphorylated and associates with Src family protein tyrosine kinases (PTKs) as well as spleen tyrosine kinase (Syk). PTKs and Syk are associated with BCR signal transduction.

Associated Disease

TCR Vector Products Product list:

Catalog Target Target
Species
Antibody
Clone
scFv-Host
Animal
Vector
length
Vector
Type
Epitope Format HLA Data
sheet
Price
TCR-C108Z LMP2 EBV 8 Human ~8kb Lentiviral RRRWRRLTV Single-chain HLA-B*2709 Inquiry
TCR-C109Z LMP2 EBV NB20 Human ~8kb Lentiviral CLGGLLTMV Non-modified HLA-A2 Inquiry
TCR-C110Z LMP2 EBV PL5.05 Human ~8kb Lentiviral CLGGLLTMV Non-modified HLA-A2 Inquiry
TCR-C111Z LMP2 EBV PL5.04 Human ~8kb Lentiviral LLWTLVLL Non-modified HLA-A2 Inquiry
TCR-C112Z LMP2 EBV Murinized ~8kb Lentiviral CLGGLLTMV Murinized and Codon-optimized and Cysteine-modi?ed HLA-A2 Inquiry
TCR-L015 LMP2 EBV Human 3817bp retroviral vector FLRGRAYGL Codon optimized and cysteine modified TCR HLA-B8 Inquiry
TCR-L055Z LMP2 EBV Human 8kb Lentiviral CLGGLLWT Non-modified HLA-A2 Inquiry
TCR-L056 LMP2 EBV Human 8200bp retroviral vector CLGGLLWT Non-modified TCR HLA-A2 Inquiry
TCR-L056Z LMP2 EBV Human 8kb Lentiviral CLGGLLTMV Non-modified HLA-A0201 Inquiry
TCR-L057 LMP2 EBV Human 3817bp retroviral vector CLGGLLTMV Non-modified TCR HLA-A0201 Inquiry
TCR-L323 LMP2 EBV Human ~8kb Lentiviral CLGGLLTMV Non-modified HLA-A0201 Inquiry

TCR Viral Particles Product list:

Catalog Target
Species
Antibody
Clone
scFv-Host
Animal
Packaging
System
Epitope Format Titer Data
sheet
Price
VP-TCR-C207 EBV 8 Human Lentivirus RRRWRRLTV Single-chain TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C208 EBV NB20 Human Lentivirus CLGGLLTMV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C209 EBV PL5.05 Human Lentivirus CLGGLLTMV Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C210 EBV PL5.04 Human Lentivirus LLWTLVLL Non-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C211 EBV Murinized Lentivirus CLGGLLTMV Murinized and Codon-optimized and Cysteine-modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C212 EBV Human Lentivirus FLRGRAYGL Codon optimized and cysteine modified TCR > 10⁷ IFU/ml Inquiry
VP-TCR-C216 EBV Human Lentivirus CLGGLLTMV Non-modified TCR > 10⁷ IFU/ml Inquiry
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