All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
VivoCAR™ Anti-5T4 (H8-C) h(CD28-41BB-CD3z) CAR circRNA integrates the potent H8 chimeric ScFv into our advanced circular RNA platform to target the oncofetal antigen 5T4 with high structural rigidity. In the context of in vivo CAR-T therapy, the H8 chimeric clone is highly significant for its robust antigen-binding kinetics, which ensures immediate and forceful T-cell activation upon expression in the tumor microenvironment. This product is specifically designed to leverage the high translation efficiency of circRNA, providing a steady pulse of CAR expression that overcomes the immunosuppressive barriers of 5T4-positive solid tumors. It serves as a powerful tool for researchers requiring a highly reactive and reliable "on-switch" for transient in vivo immune redirection against complex carcinomas.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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