PTP Pep-LNP

Cat. No.: TDLD-0825-LD83

PTP Pep-LNP

PTP Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the PTP peptide, this LNP leverages its unique ability to specifically target pancreatic ductal adenocarcinoma by binding to galectin-1, a lectin that is aberrantly localized on the cell membrane surface during pancreatic cancer development, facilitating selective accumulation at the tumor site. Our LNP is prepared using DSPE-PEG-PTP and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of PTP Pep-LNP include research in targeted pancreatic cancer therapy, developing novel diagnostic tools for pancreatic cancer, and investigating the role of galectin-1 in pancreatic tumorigenesis and progression. Please note that this product is intended for research purposes only.