YSA Pep-LNP

Cat. No.: TDLD-0825-LD97

YSA Pep-LNP

YSA Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the YSA peptide, a short sequence that specifically recognizes and binds the EphA2 receptor, this LNP offers enhanced specificity for cells overexpressing EphA2, which is prevalent in various tumors such as breast, prostate, and pancreatic cancer. Our LNP is prepared using DSPE-PEG-YSA and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of YSA Pep-LNP include targeted therapy for EphA2-overexpressing cancers, developing EphA2-specific imaging agents, studying the role of EphA2 signaling in tumor biology, and evaluating novel anti-cancer strategies. Please note that this product is intended for research purposes only.