The vector of anti-CD23 chimeric antigen receptor (CAR) is constructed for the engineering of T cells to target human CD23. The T cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-CD23 antibody linked to CD3-zeta signaling domains. And the vector product was designed for the treatment of chronic lymphocytic leukemia (CLL).
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|CAR-MZ209||Anti-CD23 (C11) h(CD28-OX40-CD3ζ) CAR, pCDCAR1|
|CAR-MZ208||Anti-CD23 (C11) h(CD28-41BB-CD3ζ) CAR, pCDCAR1|
|CAR-T-3-M309-2XZ||Anti-CD23 scFv h(CD28-OX40-CD3ζ) CART, pCDCAR1|
|CAR-T-3-M309-2BZ||Anti-CD23 scFv h(CD28-41BB-CD3ζ) CART, pCDCAR1|
|CAR-T-2-M309-2G||Anti-CD23 scFv h(CD28-FcεRIγ) CART, pCDCAR1|
|VP-CAR-LC240||Lenti-CD23 CAR (scFv-CD8-CD3ζ, Tü1) Viral Particle|
|CAR-MZ206||Anti-CD23 (C11) h(CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC895||Lenti-CD23 CAR (scFv-CD3ζ, C11) Viral Particle|
|VP-CAR-LC233||Lenti-CD23 CAR (scFv-CD28, Tü1) Viral Particle|
|VP-CAR-LC234||Lenti-CD23 CAR (scFv-FcεRIγ, Tü1) Viral Particle|
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