Claudin 18.2 CAR mRNA-LNP
Cat. No.: TDLD-0825-LD46
Claudin 18.2 CAR mRNA-LNP
Claudin 18.2 CAR mRNA-LNP is a state-of-the-art messenger RNA (mRNA) lipid nanoparticle (LNP) system, specifically engineered for efficient in vitro and in vivo protein expression. This LNP encapsulates mRNA encoding the Chimeric Antigen Receptor (CAR) targeting Claudin 18.2 (CLDN18.2), serving as an excellent tool for investigating novel CAR-T cell therapies against CLDN18.2-expressing gastric, pancreatic, and other solid tumors, enabling studies on targeted immune interception and tumor microenvironment modulation. Engineered with a proprietary lipid formulation for optimal mRNA encapsulation and delivery, it ensures high translation efficiency. Our LNP ensures uniform particle size, high encapsulation efficiency, stability, and effective delivery. Applications of Claudin 18.2 CAR mRNA-LNP include evaluating CAR expression on engineered T cells and assessing their cytotoxic activity against CLDN18.2-positive cancer cell lines. Please note that this product is intended for research purposes only.
| Payload Type | CAR mRNA |
| Payload | Claudin 18.2 CAR mRNA |
| Modification | Unmodified; N1-methyl-pseudouridine; 5-methoxyuridine; Other |
| Module Type | Unconjugation |
| Lipid Formulation | SM102 |
| Dye | Unlabeled |
| Application | Gene Therapy; CAR-T |
| Format | Liquid |
| Concentration | 0.1 mg/mL; 0.2 mg/mL; Other (Please Specify) |
| Size | 65-120 nm |
| PDI | < 0.2 |
| Zeta | ± 20.0 mV |
| Encapsulate Efficiency | >90% |
| Shipping | Dry Ice |
| Storage | Store at -80°C |
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