CPP Pep-LNP

Cat. No.: TDLD-0825-LD100

CPP Pep-LNP

CPP Pep-LNP is a state-of-the-art peptide-functionalized lipid nanoparticle (LNP), designed for efficient targeted delivery of therapeutic cargoes such as siRNA, mRNA, DNA, small molecule drugs, and RNA-guided gene editing systems. Engineered with the CPP peptide, a short cationic peptide known for its high efficiency in traversing cellular membranes, this LNP facilitates the direct internalization of the encapsulated payload into the cytoplasm and potentially the nucleus, bypassing reliance on traditional endocytosis pathways. Our LNP is prepared using DSPE-PEG-CPP and a variety of optional lipid formulations including DLin-MC3-DMA, LP-01, ALC-0315, SM102, and others. These formulations are carefully selected to ensure the LNP has uniform particle size, high encapsulation efficiency, stability, and targeted delivery. Applications of CPP Pep-LNP include overcoming cellular uptake barriers for large molecules, delivering nucleic acids or drugs directly to the cytoplasm or nucleus for enhanced efficacy, studying intracellular trafficking mechanisms, and developing novel non-viral gene therapy or drug delivery platforms. Please note that this product is intended for research purposes only.