Vaccines for Virus from Circoviridae Family

With the development of various biotechnology, vaccines play an increasingly important role in the prevention and control of diseases. Creative Biolabs has been committed to the development of vaccine technology for many years, providing a wide range of quality services to customers around the world.

Vaccines for Virus from Circoviridae Family - Creative Biolabs

Circoviridae Family

Members of the Circoviridae family are small, non-enveloped ssDNA viruses with a circular genome of approximately 2 kb, including the genera Circovirus and Gyrovirus. A proposal was recently made to add a new genus Cyclovirus to the Circoviridae family. Circovirus disease is associated with various diseases of pigs and birds. To date, Gyrovirus have not been clearly shown to cause disease, but some species have been detected in the cerebrospinal fluid of patients with neurological diseases and respiratory secretions in infants with respiratory diseases.

Vaccines for Chicken Anemia Virus

Chicken anemia virus (CAV) belongs to the genus Gyrovirus of the Circoviridae family. It is a small, non-enveloped virus that is resistant to heat inactivation and lipid solvents as well as many common disinfectants. CAV infection is economically significant because the vertical transmission of eggs from infected breeder flocks can lead to increased infant mortality. In addition, the virus alone or in combination with other pathogens has the potential to induce immune dysfunction. Vaccines play an important role in the prevention and control of CAV. In addition to commercial non-attenuated and attenuated vaccines, DNA vaccines and subunit vaccines provide effective protection and are therefore expected to be candidates for new CAV vaccines.

Vaccines for Porcine Circovirus 2

Porcine circovirus type 2 (PCV-2) is a member of the Circoviridae family of the genus Circovirus, a non-enveloped single-stranded DNA virus with a circular genome. It is considered to be one of the major pathogens causing porcine circovirus-associated disease (PCVAD), which includes several syndromes, including post-weaning multisystemic wasting syndrome (PWMS), porcine dermatitis and nephrotic syndrome (PDNS), and porcine respiratory disease syndrome (PRDC) and has caused enormous economic losses in the global pig industry. In addition to strengthening management measures, the most effective way to prevent and control PCV-2 is vaccination. By 2012, there are a total of 5 commercial vaccines, but there are some restrictions in commercial vaccines. Therefore, it is necessary to develop new vaccines and adjuvants to effectively prevent and control PCV-2.

Empowered by leading technology and years of experience in the viral vaccine, Creative Biolabs has an advanced vaccine platform that provides reasonable methods to design vaccines with high efficiency and no adverse reactions.


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