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Anti-AKAP13 Q285K T cell receptor (YC01), pCDTCR1 (TCR-YC0078)


All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

The vector of anti-AKAP13 Q285K T cell receptor (TCR) is constructed for the engineering of T cell to target A-kinase anchor protein 13 isoform 1 (KLMNIQQKL) restricted by HLA-A*02:01. The T cells are genetically modified through transduction with a lentiviral vector expressing AKAP13 Q285K-specific T cell receptor.

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Details

  • Target
  • AKAP13 Q285K
  • Epitope
  • KLMNIQQKL
  • Format
  • Non-Modified TCR
  • Allele
  • HLA-A*02:01
  • Targeting Diseases
  • Skin melanoma
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~ 8 kb
  • Vector Type
  • Lentiviral vector
  • TCR Clone
  • YC01
  • Host Species
  • Human

Target

  • Introduction
  • A-kinase anchor protein 13 is an protein that in humans is encoded by the AKAP13 gene. This protein is also called AKAP-Lbc because it encodes the lymphocyte blast crisis (Lbc) oncogene, and ARHGEF13/RhoGEF13 because it contains a guanine nucleotide exchange factor (GEF) domain for the RhoA small GTP-binding protein.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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