Anti-ITGB3 T cell receptor, pCDTCR1 (TCR-ZP329)

The vector of anti-ITGB3 T cell receptor (TCR) is constructed for the engineering of T cell to target Human. The T cells are genetically modified through transduction with a lentiviral vector expressing ITGB3-specific T cell receptor. And the vector product was designed for the treatment of Breast cancer.

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  • Target
  • ITGB3
  • Target Species
  • Human
  • Epitope
  • Format
  • Non-modified
  • Allele
  • HLA-DRB3*01:01
  • Targeting Cell Type
  • T cell
  • Targeting Diseases
  • Breast cancer
  • Vector Name
  • pCDTCR1
  • Vector Length
  • ~8kb
  • Vector Type
  • Lentiviral vector
  • TCR Clone
  • D8T64
  • Host Species
  • Human


  • Introduction
  • The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell surface mediated signalling.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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