Anti-MMP3 DNA-encoded mAb (DMAb), pVAX1 (DMAb-2325-FY)

Datasheet

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This product is the plasmid containing an encoded anti-MMP3 DMAb sequence. The plasmid can drive transcription and in vivo translation of the desired antibody.

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Specifications

Target
MMP3

Vector Name
pVAX1

Vector Description
pVAX1 was originally designed for the development of DNA vaccines. Its eukaryotic DNA sequences limited to the expression of desired sequence so that minimize the possibility of chromosomal integration. This vector has been widely used for the construction of DMAb plasmid.

Vector Promoter
CMV

Vector Tag or Fusion
Untagged

Delivery Method
Transfection

Cloning Method
Restriction Enzyme ⁄ MCS

Constitutive or Inducible System
Constitutive

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term.

Background
DNA-encoded mAb (DMAb) technology is a novel approach for a direct in vivo production of desired biologically active immunoglobulins according to the plasmid DNA delivery into tissue where the delivered plasmid containing an encoded antibody sequence. Compared with the traditional mAb, DMAb can be functionally equivalent with additional advantages such as expression profiles, glycosylation, as well as no reliance on in vivo tissue culture and costly or time-consuming production systems. The DMAb technology may provide a novel, simple, less frequent, cost-effective approach for therapeutics.

Target

Entrez Gene ID
4314

UniProt ID
P08254

Sub CAT.	DMAb Clone	DMAb Host	Target Species	DMAb Isotype	DMAb Immunogen
DMAb-2325-FY	SB14d	Mouse	Human	IgG2a
DMAb-2326-FY	CBFYM-0171	Mouse	Human	IgG1
DMAb-2327-FY	CBFYM-0277	Rabbit	Mouse	IgG
DMAb-2328-FY	CBFYM-0415	Mouse	Human	IgG1	Human stromelysin 1 (SL 1)
DMAb-2329-FY	CBFYM-0521	Mouse	Rat	IgG
DMAb-2330-FY	CBFYM-0683	Mouse	Human	IgG1
DMAb-2331-FY	CBFYM-0684	Mouse	Human	IgG1, k
DMAb-2332-FY	CBFYM-0685	Mouse	Rabbit	IgG1, k
DMAb-2333-FY	CBFYM-0686	Mouse	Human	IgG1, k
DMAb-2334-FY	CBFYM-0687	Mouse	Human	IgG2a
DMAb-2335-FY	CBFYM-0688	Mouse	Human	IgG2b
DMAb-2336-FY	CBFYM-0689	Mouse	Human	IgG2b
DMAb-2337-FY	CBFYM-2399	Mouse	Human	IgG1	Chinese hamster ovary cell line CHO-derived recombinant human MMP-3
DMAb-2338-FY	CBFYM-2400	Mouse	Human	IgG2b
DMAb-2339-FY	CBFYM-2401	Mouse	Human	IgG1	Recombinant fragment of human MMP3 expressed in E. coli
DMAb-2340-FY	CBFYM-2402	Mouse	Human	IgG2b, k	Recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: GAARGEDTSM NLVQKYLENY YDLKKDVKQF VRRKDSGPVV KKIREMQKFL GLEVTGKLDS DTLEVMRKPR CGVPDVGHFR TFPGIPKWRK THLTYRIVNY TPDLPKDAVD
DMAb-2341-FY	CBFYM-2403	Mouse	Human	IgG1	Ovalbumin conjugated synthetic peptide corresponding to a region within the C-terminus of human MMP-3
DMAb-2342-FY	CBFYM-2404	Mouse	Human	IgG2b	APMA (4-Aminophenylmercuric acetate) activated Human stromelysin-1
DMAb-2343-FY	CBFYM-2405	Rabbit	Human	IgG	Recombinant protein
DMAb-2344-FY	CBFYM-2406	Rat	Mouse	IgG2a	Mouse myeloma cell line NS0-derived recombinant mouse MMP-3, Tyr18-Cys477
DMAb-2345-FY	CBFYM-2407	Mouse	Rat	IgG
DMAb-1591-CQ	CBXS-0046	Mouse			Matrix Metalloproteinase 3
DMAb-1592-CQ	CBXS-0047	Mouse	Rat		Matrix Metalloproteinase 3

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Anti-MMP3 DNA-encoded mAb (DMAb), pVAX1 (DMAb-2325-FY)

Specifications

Target

Customer Reviews and Q&As

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