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DDB2

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

DDB2 is a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YC0370 Anti-DDB2 (1F11) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 1F11 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC0371 Anti-DDB2 (2246C4a) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 2246C4a Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC0372 Anti-DDB2 (8C100) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 8C100 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC0373 Anti-DDB2 (11C1023) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human 11C1023 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC0374 Anti-DDB2 (D4C4) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human D4C4 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC0375 Anti-DDB2 (CBYCD-202) h(scFv-41BB-CD3ζ) CAR, pCDCAR1 Human CBYCD-202 Rabbit scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1270 Anti-DDB2 (1F11) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 1F11 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1271 Anti-DDB2 (2246C4a) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 2246C4a Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1272 Anti-DDB2 (8C100) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 8C100 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1273 Anti-DDB2 (11C1023) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human 11C1023 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1274 Anti-DDB2 (D4C4) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human D4C4 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YC1275 Anti-DDB2 (CBYCD-202) h(scFv-CD28-CD3ζ) CAR, pCDCAR1 Human CBYCD-202 Rabbit scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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