HGF

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss. [provided by RefSeq, Nov 2015]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP116 HGF (CD44 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human HGF-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP724 HGF (MET Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human HGF-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1516 HGF (CD44 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human HGF-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2124 HGF (MET Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human HGF-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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