IL23A

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This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq, Jul 2008]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP833 IL23A (IL12RB1 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL23A-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP834 IL23A (IL23R Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL23A-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2233 IL23A (IL12RB1 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL23A-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2234 IL23A (IL23R Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL23A-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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