IL31

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM, Mar 2008]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP842 IL31 (IL31RA Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL31-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP843 IL31 (OSMR Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL31-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2242 IL31 (IL31RA Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL31-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2243 IL31 (OSMR Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human IL31-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-0723-LX48 Anti-cIL31 (E12) c(CD28-41BB-CD3ζ) CAR, pCDCAR1 Vector Canine E12 scFv-CD28-41BB-CD4ζ Lentiviral vector T cell CAR-T   Add to Cart   Datasheet
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