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RBP3

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively. [provided by RefSeq, Jul 2008]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-CN099 Anti-RBP3 (4F3) h(CD28-CD3ζ) CAR, pCDCAR1 Human 4F3 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CN100 Anti-RBP3 (CBCNR-327) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBCNR-327 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CN101 Anti-RBP3 (CBCNR-328) h(CD28-CD3ζ) CAR, pCDCAR1 Human CBCNR-328 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CN200 Anti-RBP3 (4F3) h(41BB-CD3ζ) CAR, pCDCAR1 Human 4F3 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CN201 Anti-RBP3 (CBCNR-327) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBCNR-327 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-CN202 Anti-RBP3 (CBCNR-328) h(41BB-CD3ζ) CAR, pCDCAR1 Human CBCNR-328 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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