RSPO1

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This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
XS-1222-ZP174 RSPO1 (ZNRF3 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human RSPO1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1111 RSPO1 (LGR4 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human RSPO1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1112 RSPO1 (LGR5 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human RSPO1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1113 RSPO1 (LGR6 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human RSPO1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1114 RSPO1 (LRP6 Receptor) h(CD28-CD3ζ) Ligand-based CAR, pCDCAR1 Human RSPO1-CD28-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP1574 RSPO1 (ZNRF3 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human RSPO1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2511 RSPO1 (LGR4 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human RSPO1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2512 RSPO1 (LGR5 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human RSPO1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2513 RSPO1 (LGR6 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human RSPO1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
XS-1222-ZP2514 RSPO1 (LRP6 Receptor) h(41BB-CD3ζ) Ligand-based CAR, pCDCAR1 Human RSPO1-41BB-CD6ζ Lentiviral vector T cell   Add to Cart   Datasheet
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