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TRIM68

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.

TRIM68 is a member of the tripartite motif-containing protein family, whose members are characterized by a "really interesting new gene" (RING) finger domain, a zinc-binding B-box motif, and a coiled-coil region. Members of this family play a role as E3 ubiquitin ligases and are involved in a broad range of biological processes. TRIM68 regulates the activation of nuclear receptors, such as androgen receptor, and has been implicated in development of prostate cancer cells, where its expression increases in response to a downregulation of microRNAs. In addition, TRIM68 participates in viral defense regulation as a negative regulator of interferon-beta.
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CAT Product Name Target Species Antibody Clone Antibody Host Receptor Construction Vector Type Targeting Cell Type CAR Vector Type Inquiry & Datasheet
CAR-YJ381 Anti-TRIM68 (5G2) h(41BB-CD3ζ) CAR, pCDCAR1 Human 5G2 Mouse scFv-41BB-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
CAR-YJ881 Anti-TRIM68 (5G2) h(CD28-CD3ζ) CAR, pCDCAR1 Human 5G2 Mouse scFv-CD28-CD3ζ Lentiviral vector T cell   Add to Cart   Datasheet
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