Fluorescein isothiocyanate (FITC) is a synthetic dye that is physiologically deficient in human body and has been used widely as a flowcytometry marker to label antibodies. The anti-FITC CAR contains two essential elements, one is a FITC-tagged tumor-targeting switch molecule and the other is a transmembrane CAR with an anti-FITC scFv. The FITC-labeled switch molecules form a pseudo-immunological synapse between anti-FITC CAR T cells and tumor cells expressing a given antigen, such as folate receptor or CD19, leading to lysis of the corresponding tumor cells.
Creative Biolabs provides customized Anti-FITC CAR design and construction services. Please contact us for more detailed information.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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