Anti-TRRAP T cell receptor (T7), pCDTCR1(TCR-L220)

The vector of anti-TRRAP T cell receptor (TCR) is constructed for the engineering of T cell to target Human TRRAP. The T cells are genetically modified through transduction with a lentiviral vector expressing TRRAP-specific T cell receptor. And the vector product was designed for the treatment of Breast cancer.


Details


Target
TRRAP
Target Species
Human
Epitope
KLVFGSVFL
Format
Non-modified
HLA
HLA-A201
Targeting Diseases
Breast cancer
Vector Name
pCDTCR1
Vector Length
~8kb
Vector Type
Lentiviral
Antibody Clone
T7
Antibody Host
Human

Target


Gene Name
transformation/transcription domain associated protein
Official Symbol
TRRAP
Gene ID
UniProt ID
Synonyms
Tra1; TR-AP; PAF400; STAF40; PAF350/400
Introduction
This gene encodes a large multidomain protein of the phosphoinositide 3-kinase-related kinases (PIKK) family. The encoded protein is a common component of many histone acetyltransferase (HAT) complexes and plays a role in transcription and DNA repair by recruiting HAT complexes to chromatin. Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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Carcinoma

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Tel: 1-631-871-5806
Fax: 1-631-207-8356
Email:

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