Insr

This gene encodes a member of the receptor tyrosine kinase family of transmembrane signaling proteins that play important roles in cell differentiation, growth and metabolism. The encoded preproprotein undergoes proteolytic processing to generate alpha and beta chains that form a disulfide-linked heterodimer which, in turn homodimerizes to form a mature, functional receptor. Mice lacking the encoded protein develop severe hyperglycemia and hyperketonemia, and die within a couple of days after birth as a result of diabetic ketoacidosis.

Associated Disease
  • Type 1 diabetes

TCR Vector Products Product list:

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Antibody
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Vector
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TCR-C104Z Insr Mouse 2C Mouse ~8kb Lentiviral GNYSFYAL Non-modified H-2Kb Inquiry

TCR Viral Particles Product list:

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Packaging
System
Epitope Format Titer Data
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Price
VP-TCR-C205 Mouse 2C Mouse Lentivirus GNYSFYAL Non-modified TCR > 10⁷ IFU/ml Inquiry
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