RPS4Y

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, X-linked (RPS4X). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Associated Disease
  • Graft versus host disease (GvHD)

TCR Vector Products Product list:

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TCR-C225Z RPS4Y Human YKIII.8 Mouse ~8kb Lentiviral TIRYPDPVI Non-modified HLA-B*5201 Inquiry

TCR Viral Particles Product list:

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VP-TCR-C468 Human YKIII.8 Mouse Lentivirus TIRYPDPVI Non-modified TCR > 10⁷ IFU/ml Inquiry
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