All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
VivoCAR™ Anti-HAVCR2 (h22E11) h(CD28-41BB-CD3z) CAR circRNA features the h22E11 humanized ScFv, specifically engineered for precision-guided in vivo engineering of effector lymphocytes. The importance of the h22E11 clone lies in its distinct epitope specificity, which allows for the selective targeting of TIM-3+ populations without interfering with essential homeostatic immune functions. Combined with the circRNA platform's superior stability and translation efficiency, this product enables a controlled, transient therapeutic pulse. This makes it an ideal candidate for repeat-dosing strategies aimed at clearing persistent leukemic stem cells and overcoming the immunosuppressive "cold" tumor microenvironment.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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