The vector of anti-EGFRvIII chimeric antigen receptor (CAR) is constructed for the engineering of NK cells to target human EGFRvIII. The NK cells are genetically modified through transduction with a lentiviral vector expressing scFv of anti-EGFRvIII antibody linked to DAP12 signaling domains. And the vector product was designed for the treatment of Glioblastoma.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
|VP-CAR-LC199||Lenti-EGFRvIII CAR (scFv-CD3ζ, RAbDMvIII) Viral Particle|
|CAR-MZ086||Anti-EGFRvIII (13.1.2) h(CD28-41BB-CD3ζ) CAR, pCDCAR1|
|CAR-T-1-L338-Z||Anti-EGFR scFv h(CD3ζ) CART, pCDCAR1|
|CAR-T-2-L338-2Z||Anti-EGFR scFv h(CD28-CD3ζ) CART, pCDCAR1|
|VP-CAR-LC836||Lenti-EGFRvIII CAR (scFv-CD3ζ, MR1.1) Viral Particle|
|CAR-MZ166||Anti-EGFRvIII (MR1-1) h(CD3ζ) CAR, pCDCAR1|
|CAR-MZ068||Anti-EGFRvIII (3C10) h(OX40-CD3ζ) CAR, pCDCAR1|
|CAR-LC099||Anti-EGFR (806) h(41BB-CD3ζ) CAR, pCDCAR1|
|VP-CAR-LC200||Lenti-EGFRvIII CAR (scFv-CD28-FcεRIγ, RAbDMvIII) Viral Particle|
|VP-CAR-LC205||Lenti-EGFRvIII CAR (scFv-41BB-CD3ζ, RAbDMvIII) Viral Particle|
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