All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
VivoCAR™ Anti-c-Met (5D5.v2) h(CD28-41BB-CD3z) CAR circRNA leverages the optimized 5D5.v2 humanized ScFv to provide a refined tool for safe and repeatable in vivo immune engineering. The importance of the 5D5.v2 clone lies in its improved biophysical properties and reduced immunogenicity, making it ideal for the long-term management of metastatic disease through multiple circRNA-LNP injections. This product utilizes the stable circRNA scaffold to achieve persistent CAR expression on circulating lymphocytes, offering a highly tolerable therapeutic strategy for targeting c-Met-positive lineages while preventing host-mediated immune clearance.
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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