Creative Biolabs

RNA-LNP Encapsulation Assay Kit

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Cat. No.: TDLD-0825-LD7

RNA-LNP Encapsulation Assay Kit

This product is a RiboGreen-based assay kit for determining the encapsulation efficiency of RNA within Lipid Nanoparticles (LNPs). The core of this assay relies on the specific fluorescence enhancement of RiboGreen dye upon binding to RNA.While the free dye itself is nearly non-fluorescent, its interaction with RNA produces a strong, linear signal detectable at Ex/Em:490/525 nm. This allows for a straightforward calculation of encapsulation efficiency by comparing the signal from total RNA against the signal from free, unencapsulated RNA. Please note that this product is intended for research purposes only.

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For Research Use Only. Not for Diagnostic or Treatment Applications.
Kit Type Encapsulation Assay Kit
Components RiboGreen Dye, RNA-LNP Reference Material, Buffer
Application Encapsulation Efficiency

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Creatibe Biolabs' custom LNP was the only solution that successfully delivered our CRISPR-Cas9 payload across the blood-brain barrier with high efficiency and low toxicity.”

Dr. Evelyn Reed

Postdoctoral Researcher, Leading University

Our siRNA candidate was failing due to off-target toxicity, but Creatibe Biolabs' team rapidly redesigned our LNP using their modular platform, rescuing our preclinical program.”

Ben Carter

Project Manager

Achieving cytosolic delivery of our protein degrader with Creatibe Biolabs' exosome platform was the key to unlocking our candidate's full therapeutic potential.”

Dr. Kenji Tanaka

Principal Scientist, Large Pharma Corp

Our oncology drug's efficacy was limited by poor tumor accumulation. Creatibe Biolabs' peptide-conjugated liposomes provided the precise targeting we needed, dramatically increasing the drug's therapeutic index.”

Dr. Clara Schmidt

Senior Scientist, Oncology Innovations Inc.

We required a delivery system that would only release its payload in the tumor's acidic microenvironment. Creatibe Biolabs' pH-responsive liposomes performed flawlessly, minimizing systemic exposure.”

David Chen

Formulation Scientist

Outstanding expertise in antibody engineering.The team's attention to detail and innovative approaches have sianificantly accelerated our development timeline.

Sarah L.

Senior Research Scientist

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