ABCC5 Analysis - Creative Biolabs

ATP-binding cassette subfamily C member 5 (ABCC5), as known as MRP5, is an ATP-binding cassette (ABC) transporter encoded by the ABCC5 gene. Creative Biolabs offers various ABCC5 analysis services and customized services for global clients. Our highly professional R&D team and rich service experience can provide you with satisfactory services.

Scientific Validity

Studies indicated that ABCC5 could mediate the transmembrane transport of cyclic nucleotides or nucleotide analogs. Meanwhile, the structure of the ABCC5 protein is very similar to that of ABCC4 as shown in Figure 1. Since ABCC5 plays an important role in the intracellular and extracellular transport of nucleic acid molecules, the mutation and abnormal expression of ABCC5 gene may increase the susceptibility of the human body to certain diseases and the resistance of cells.

Topology of ABCC5 Fig.1 Structure of ABCC5.¹

ABCC5 Gene and Cancer Treatment

Numerous studies have confirmed that ABCC transporters are associated with acquired drug resistance in a variety of cancers. Scientists used pan-cancer analysis and single-cell analysis to find that ABCC5 expression was up-regulated in HCC, and it was related to immune cell infiltration and immune cell differentiation of HCC. They also found that ABCC5 is abnormally expressed in many cancers. These studies suggest that the ABCC5 gene is strongly associated with cancer growth.

Services at Creative Biolabs

Creative Biolabs provides comprehensive analysis services and in vitro and in vivo assays tailored to the ABCC5 gene and the protein encoded by it. At Creative Biolabs, we provide various first-rate analysis services for the ABCC5.

ABCC5 level test (ELISA, LFA, CLIA, LEIA, etc.)
Western blot assay
ABCC5 protein sequencing
ABCC5 gene test (DNA sequencing, ISH, etc.)
Other customized ABCC5 analysis services

Creative Biolabs is a renowned biotechnology company that provides various types of target analysis services, target screening services, and drug development services. In addition, we also provide research services on the correlation between ABCC5 gene expression levels and cancer cell resistance to novel anti-cancer drugs. Creative Biolabs is your best choice for quality partners.