Conventional Liposome Development Service

Liposomes are the most common and well-studied nanocarriers for targeted drug delivery. They have improved therapies in a series of biomedical applications by stabilizing the therapeutic compounds, overcoming obstacles to cell and tissue uptake, and improving the biodistribution of the compounds at targeted sites in vivo. Combining advanced preparation technologies for various liposomes, Creative Biolabs provides customized services for conventional liposome formulation design and drug encapsulation.

Introduction to Conventional Liposomes

Conventional liposomes are the first generation of liposomes. They are a family of vesicle structures based on a lipid bilayer surrounding aqueous compartments, which can be composed of cationic, anionic or neutral (phosphate) lipids and cholesterol. Conventional liposomes formulations are mainly composed of natural phospholipids or lipids, such as 1,2-distearyl-sn-glycerin-3-phosphatidylcholine (DSPC), sphingomyelin, lecithin and monosialoganglioside.

Fig.1 Structure of conventional liposome

Applications of Conventional Liposomes

Based on the fact that conventional liposomes are easily captured by macrophages, most of them can be used to treat diseases of macrophage system. In addition, macrophages are the habitat of many fungi and parasites, and conventional liposomes can target the macrophages to treat infectious diseases, such as visceral Leishmaniasis. Moreover, conventional liposomes are also mostly used as vaccine adjuvants to transport antigenic substances to the circulatory system, thus enhancing the immune  response.

What We Can Do about Conventional Liposome Development?

Creative Biolabs has more than ten years of experience in liposome formulation development. We integrate the knowledge of well-known liposome scholars into our liposome technology. Our ground-breaking research, objectified working processes, and state-of-the-art equipment all mean that we are able to develop distinctive liposomal formulations and products.

• Quickly, customized and easily liposome production and optimization
• Functionality is rationally designed to improve drug delivery efficiency
• Seamless way to scaling up production
• Control liposome size through instrument parameters
• Reproducible conditions for liposome production
• No cross-contamination liposomes are produced in disposable autoclaved containers

For more details about our services, please directly contact us.

For Research Use Only. Not For Clinical Use