Recombinant HHV-5 (strain AD169) Membrane glycoprotein US3 (US3), E. coli, Biotin conjugation (CAT#: GPX-087-EB-J)

Product Overview	Recombinant Human herpesvirus 5 (strain AD169) (HHV-5) Membrane glycoprotein US3 was expressed in E. coli with a His-tag or Tag free. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity	Determined by its binding ability in a functional ELISA.
Source	E. coli
Species	Human herpesvirus 5 (strain AD169) (HHV-5)
Tag	His-tag or Tag free
Purity	>90%, determined by SDS-PAGE.
Conjugation	Biotin

Target	US3
Full Name	Membrane glycoprotein US3
Uniprot ID	P09712
Background	Retains, but does not degrade MHC class I heterodimers in the endoplasmic reticulum during the immediate-early period of virus infection, thereby impairing their transport and maturation. Forms a complex with beta-2-microglobulin-associated class I heavy chains, which accumulate in the ER. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes.
Alternate Names	Membrane glycoprotein US3; Glycoprotein E; Protein HQLF1; gpUS3 IE