Flavonoid Quantitative Analysis Service: Unlocking Nature's Chemical Diversity
Are you currently facing challenges in precisely characterizing natural product extracts, validating bioactivity claims, or standardizing botanical ingredients? Our flavonoid quantitative analysis service helps you accelerate natural product development, obtain accurate phytochemical profiles, and ensure product quality through advanced analysis technologies and expert interpretation. Flavonoids are a diverse group of plant secondary metabolites, widely recognized for their significant biological activities, including potent antioxidant, anti-inflammatory, and medicinal properties. Found abundantly in fruits, vegetables, and medicinal plants, their precise characterization is crucial for validating health claims, ensuring product efficacy, and standardizing natural ingredients.
Steps of Flavonoid Quantitative Analysis Service
Creative Biolabs' flavonoid quantitative analysis service delivers precise, reliable data on the flavonoid composition of your samples, empowering informed decision-making in research, development, and quality control. We provide comprehensive solutions for identifying and quantifying individual flavonoid compounds, assessing total flavonoid content, and correlating chemical profiles with biological activities. Creative Biolabs is tailored to your specific needs, from broad profiling to targeted quantification.
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Total flavonoid content (TFC) analysis
This service provides a rapid and effective method to determine the overall flavonoid content in your sample, typically expressed as a common flavonoid equivalent. It's ideal for initial screening and comparative studies.
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Targeted flavonoid analysis
For projects requiring precise quantification of specific, pre-defined flavonoid compounds. This is crucial for quality control, dosage determination, and efficacy studies of known active ingredients.
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Comprehensive flavonoid analysis
This advanced service provides a holistic view of all detectable flavonoid metabolites in your sample, including known and potentially novel compounds. It's invaluable for discovering unique chemical signatures, identifying differential metabolites, and understanding complex natural matrices.
Regardless of the service type, our analysis typically follows these rigorous steps:
Sample Receipt & Extraction
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A critical step where flavonoids are selectively extracted from the sample matrix using proprietary or established solvent systems and techniques (e.g., maceration, sonication, accelerated solvent extraction).
Purification
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Depending on the complexity of the extract and the sensitivity required, crude extracts may undergo further purification steps to remove interfering substances.
Chromatographic Separation
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The extract is injected into a high-performance liquid chromatography system (HPLC) where compounds are separated according to their physicochemical properties as they pass through a stationary phase.
Detection and Quantification
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The separated compounds are captured and identified by specific detectors. The intensity of the detected signals is correlated with known concentrations of authentic standards to accurately quantify the concentration of each flavonoid.
Data Analysis & Reporting
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Raw data is processed, and comprehensive reports are generated, including chromatograms, mass spectra, quantitative results, and expert interpretation.
Creative Biolabs is your premier partner for unlocking the full potential of natural products. Our flavonoid quantitative analysis service, backed by advanced Metabolism Analysis platforms and deep scientific expertise, provides the critical data you need for discovery, development, and quality assurance. We are dedicated to delivering precise, actionable insights that accelerate your progress. In addition, we also provide mature Organic Acid, Catechin, Biogenic Amine, Alkaloid, and Trimethylamine N-oxide quantitative analysis services. Ready to advance your natural product research or development? Our team of experts is eager to discuss your specific project needs and demonstrate how Creative Biolabs can provide tailored solutions. Please contact us to inquire about more details.
Published Data
This article delves into the intricate world of flavonoid compounds present in various citrus peels. Employing a sophisticated analysis technique known as UPLC-MS/MS, the researchers aimed to comprehensively map the flavonoid profiles of these peels. The investigation successfully identified a remarkable total of 254 distinct flavonoid metabolites across five different citrus varieties, revealing the rich biochemical diversity within this fruit group.
Fig.1 PCA analysis results of flavonoid metabolites.1
FAQs
Q1: How can Creative Biolabs' Flavonoid Quantitative Analysis Service benefit my research in drug discovery?
A1: Our service provides precise identification and quantification of flavonoids, which are often lead compounds in drug discovery. By accurately characterizing the phytochemical profile of your extracts, we help you identify potential drug candidates, understand structure-activity relationships, and streamline the preclinical development process. This precision is vital for moving from initial screening to targeted therapeutic development.
Q2: What types of samples can you analyze for flavonoid content, and what are the typical turnaround times?
A2: We are equipped to analyze a wide range of biological and botanical samples, including plant tissues (leaves, roots, flowers, fruits, peels), crude extracts, purified fractions, and even finished product formulations. The typical timeframe for our services ranges from 4 to 8 weeks, depending on the complexity and scope of your project. For specific project timelines or unique sample types, we encourage you to contact our team for a detailed discussion.
Customer Review
Exceptional Accuracy
"Using Creative Biolabs's flavonoid quantitative analysis service in our antioxidant research has significantly improved the precision of our compound identification and quantification. The detailed LC-MS/MS data allowed us to confidently correlate specific flavonoid profiles with observed cellular antioxidant activities, a level of detail crucial for our published data. Their expertise in handling complex plant matrices is unparalleled." - Ms. S. Whi***e
Unlocking New Discoveries
"The in-depth analysis provided by Creative Biolabs allowed us to discover unique flavonoid metabolites in a previously uncharacterized plant species. Their team's guidance on sample preparation and data interpretation was invaluable, helping us identify compounds with potential novel bioactivities that we are now pursuing for pharmaceutical applications. This partnership has truly accelerated our bioprospecting efforts." - Dr. U. Cla***k
Reference
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Wang, Fu, et al. "Analysis of flavonoid metabolites in citrus peels (Citrus reticulata "Dahongpao") using UPLC-ESI-MS/MS." Molecules 24.15 (2019): 2680. DOI: 10.3390/molecules24152680. Distributed under an Open Access license CC BY 4.0, without modification.
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