Recombinant Human ANGPT1 Protein, Sia-Increased Human Cell Lines (CAT#: GLJF-0622-JF346)

Product Overview	Recombinant human ANGPT1 protein (NP_001137.2) is produced in Sia-Increased Human Cell Lines. This expression system is used for the production of glycoproteins with high sialylation and core fucosylation.
Source	Sia-Increased Human Cell Lines
Species	Human
Tag	His-tag, FC-tag
Purity	>90%, determined by SDS-PAGE.
Endotoxin Level	Regular batch
Conjugation	None

Target	ANGPT1
Full Name	Angiopoietin-1
Gene ID	284
Uniprot ID	Q15389
Accession Number	NP_001137.2
Background	This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Alternate Names	ANG-1; ANGPT1; KIAA0003