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Recombinant Human T-cell-specific surface glycoprotein CD28 (CD28) (19-152 aa) [hFc-tag], Mammalian cell

CAT#: GPX04-135J

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Specifications Target Information Related Products
Specifications
Product Overview
Recombinant HumanT-cell-specific surface glycoprotein CD28 (NP_001230006.1) (19-152 aa) was expressed in Mammalian cell with a hFc-tag at the C-terminus. The biological activity was determined by its binding ability in a functional ELISA. This product can be used in ELISA, WB, and IP.
Biological Activity
Determined by its binding ability in a functional ELISA.
Source
Mammalian cell
Species
Human
Fragment
19-152 aa
Sequence
NKILVKQSPMLVAYDNAVNLSCKYSYNLFSREFRASLHKGLDSAVEVCVVYGNYSQQLQVYSKTGFNCDGKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPPPYLDNEKSNGTIIHVKGKHLCPSPLFPGPSKP
Tag
hFc-tag at the C-terminus
Predicted MW
44.1 kDa
Purity
>90%, determined by SDS-PAGE.
Conjugation
Unconjugated
Target Information
Target
CD28
Full Name
T-cell-specific surface glycoprotein CD28
Gene ID
940
Uniprot ID
P10747
Accession Number
NP_001230006.1
Background
Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation.
Alternate Names
T-cell-specific surface glycoprotein CD28
For Research Use Only.
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