N-Glycan Library Products

Unlock Glycoscience: Premium N-Glycan Libraries for Discovery

N-Glycans are complex sugar chains attached to proteins, which are the indispensable molecules governing cellular communication, immune response, and protein functionality. In the rapidly expanding field of glycobiology, access to highly pure, structurally validated Glycan Standards is paramount for reliable results in drug development, biomarker discovery, and biologics quality control (QC). Our comprehensive N-glycan library products offer the essential tools needed to accelerate your research from fundamental discovery to clinical application. Creative Biolabs provides the broadest, most rigorously characterized collection of naturally occurring and synthetic N-glycans available globally.

Source pathways of N-glycans. (OA Literature) Fig.1 Diverse sources of N-glycans.¹

Structural Diversity: Visualizing the N-Glycome

The biological functions of a glycoprotein are dictated by the precise configuration of its attached glycans. Our library encompasses the full range of N-glycan heterogeneity required to decipher these complex interactions. We provide access to structures that represent all major biosynthetic pathways, as well as rare structures.

Table 1 Common N-glycan structures.

CAT#: GLJF-1125-HX259	CAT#: GLJF-1125-HX260	CAT#: GLJF-1125-HX261
CAT#: GLJF-1125-HX262	CAT#: GLJF-1125-HX263	CAT#: GLJF-1125-HX264
CAT#: GLJF-1125-HX265	CAT#: GLJF-1125-HX266	CAT#: GLJF-1125-HX267
CAT#: GLJF-1125-HX268	CAT#: GLJF-1125-HX269	CAT#: GLJF-1125-HX270
CAT#: GLJF-1125-HX271	CAT#: GLJF-1125-HX272	CAT#: GLJF-1125-HX273
CAT#: GLJF-1125-HX274	CAT#: GLJF-1125-HX275	CAT#: GLJF-1125-HX276

For more structures, please refer to our N-Glycan Library Catalog.

The Core Offering: The Comprehensive N-Glycan Standard Libraries

Creative Biolabs provides the definitive collection of N-glycan standards engineered for consistency and scientific excellence. Our N-glycan library is designed for researchers who demand precision and diversity. Each glycan is purified from natural sources or synthesized to ensure the highest purity.

Available Formats

Bulk standards: Milligram to gram quantities for large-scale functional assays or bioproduction QC.
Discovery panel: Pre-aliquoted sets of the 50 most common N-glycans for initial screening.
Custom mixes: Tailored combinations based on your specific therapeutic area (e.g., oncology, autoimmunity, virology).

Product Platforms: Accelerating Glycan Interaction Studies

Beyond purified standards, we offer specialized formats to match your specific application requirements.

High-Throughput Screening: Glycan Microarrays
Determine the binding specificity of your antibodies, lectins, proteins, or viral particles in a high-throughput format. Product: N-Glycan array Application: Identify novel glycan-binding proteins (GBPs), profile antibody cross-reactivity, and screen viral hemagglutination activity.
Analytical Tools: Fluorescently Labeled Glycans
Simplify and standardize your glycan analysis workflows with pre-labeled standards for detection via fluorescence, HPLC, or CE. Product: 2-AB, 2-AA, or APTS-labeled N-glycan standards Application: Reference standards for released N-glycan profiling, confirming structural assignments, and quantifying enzyme activity.

Key Applications in Research and Industry

Biologics & Pharmaceutical QC

Glycosylation is a critical quality attribute for therapeutic proteins as it directly impacts efficacy, immunogenicity, and pharmacokinetics. Our highly pure, structurally defined N-glycan standards are essential for the stringent regulatory landscape of biopharma.

Diagnostic Development and Biomarker Discovery

Aberrant glycosylation is a hallmark of many diseases, including cancer, autoimmune disorders, and neurodegeneration. Leveraging our comprehensive N-glycan libraries, researchers can accelerate the discovery and validation of novel glycosylation biomarkers. Our N-glycan arrays and pre-labeled standards are specifically designed to facilitate rapid, specific, and sensitive detection of changes in the glycome associated with disease onset or progression. By identifying subtle but significant shifts in glycan structures, our tools empower the creation of next-generation diagnostic assays that offer superior specificity and earlier detection capability.

Fundamental Glycoscience and Enzymatic Studies

For foundational research, having the widest possible array of defined substrates and products is non-negotiable. Our library supports essential enzymatic studies of glycosidases and glycosyltransferases, enabling researchers to precisely characterize enzyme kinetics and specificity, and to map out biosynthetic pathways. The standards are also vital for structural determination workflows and for functional analysis to probe the roles of individual glycan motifs in cellular processes, protein stability, and signaling cascades. Our commitment to providing the broadest and most accurate library ensures that scientists have the reliable tools they need to advance our fundamental understanding of glycobiology.

Request a Quote and Consultation Today

Don't let the complexity of glycoscience slow down your breakthroughs. Our expert team is ready to assist you in selecting the ideal library format or designing a custom solution tailored to your project.

Creative Biolabs offers:

Diverse glycan libraries: In addition to the N-glycan library, we also offer a variety of other types of glycan libraries, such as O-Glycan, HMO-Glycan, Mannose Glycan, Lacto Glycan, and Blood Group Antigen Libraries to global clients to accelerate your project research.
Free consultation: Discuss your specific glycobiology project with one of our lead scientists.
Volume pricing: Competitive rates for bulk orders and institutional licenses.
Custom synthesis: Need a non-standard glycan or a Specific Label? Inquire about our bespoke synthesis services.

Please contact us now to accelerate your glycoscience discovery.

Reference

Zhao, Xiaoya et al. "Recent Chemical and Chemoenzymatic Strategies to Complex-Type N-Glycans." Frontiers in Chemistry Vol 10 880128. 26 May. 2022. Distributed under an Open Access license CC BY 4.0, without modification. https://doi.org/10.3389/fchem.2022.880128