Anti-CD40L (clone 5LC8P) SynExpress C-mCh-TF-N Modified CD8+ T cells

CAT#: ITS-1224-CR1543
Clone: 5LC8P
Host: Humanized
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: CMV-mCherry-TFIIA-NotI
Carrier Type: Lentivirus
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD40L (clone 5LC8P). We employs the Lentivirus (CMV-mCherry-TFIIA-NotI) vector components and the SynExpress system of the Single base pair Knock-in/Negative feedback for a robust and sustained response against cancers.
Host
Humanized
Target
CD40L
Clone
5LC8P
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
CMV
Effector Gene
TFIIA
Insertion Sites
NotI
Gene Modification
Knock-in
Modification Domain
Single base pair
Carrier Type
Lentivirus
Transformation Accuracy
0.94
Cell Culture
Adherent Culture
Target
CD40L
Alternative Names
CD40LG; CD154; CD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP; gp39; hCD40L; CD40 ligand
Gene ID
P29965(Human); P27548(Mouse)
UniProt ID
959(Human); 21947(Mouse)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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