Anti-CD40L (clone DOM-4I) SynExpress C-Cy3-P-P Modified CD8+ T cells

CAT#: ITS-1224-CR1554
Clone: DOM-4I
Host: Human
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: CMV-Cy3-PAX-PstI
Carrier Type: pUC
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD40L (clone DOM-4I). We employs the pUC (CMV-Cy3-PAX-PstI) vector components and the SynExpress system of the DNA methylation sites Knock-in/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
CD40L
Clone
DOM-4I
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
Cy3
Promoter
CMV
Effector Gene
PAX
Insertion Sites
PstI
Gene Modification
Knock-in
Modification Domain
DNA methylation sites
Carrier Type
pUC
Transformation Accuracy
0.94
Cell Culture
Plate Culture
Target
CD40L
Alternative Names
CD40LG; CD154; CD40L; HIGM1; IGM; IMD3; T-BAM; TNFSF5; TRAP; gp39; hCD40L; CD40 ligand
Gene ID
P29965(Human); P27548(Mouse)
UniProt ID
959(Human); 21947(Mouse)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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