Creative Biolabs-Immuno-oncology

Anti-CD70 (clone RM0SQG2E4I) SynExpress C-mKa-I17-E Modified CD8+ T cells (CAT#: ITS-1224-CR1776)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target CD70 (clone RM0SQG2E4I). We employs the Adenovirus (CMV-mKate-IL-17-EcoRI) vector components and the SynExpress system of the Exons Prime Editing/Positive feedback for a robust and sustained response against cancers.
Host
Rat
Target
CD70
Clone
RM0SQG2E4I
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mKate
Promoter
CMV
Effector Gene
IL-17
Insertion Sites
EcoRI
Gene Modification
Prime Editing
Modification Domain
Exons
Carrier Type
Adenovirus
Transformation Accuracy
0.98
Cell Culture
Adherent Culture
Case Studies
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