Anti-DNMT3A (clone 1GF35L) SynExpress T7-mKa-I10-E Modified CD8+ T cells

CAT#: ITS-1224-CR2212
Clone: 1GF35L
Host: Mouse
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: T7-mKate-IL-10-EcoRI
Carrier Type: Lentivirus
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target DNMT3A (clone 1GF35L). We employs the Lentivirus (T7-mKate-IL-10-EcoRI) vector components and the SynExpress system of the Single base pair RNA Editing/Positive feedback for a robust and sustained response against cancers.
Host
Mouse
Target
DNMT3A
Clone
1GF35L
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mKate
Promoter
T7
Effector Gene
IL-10
Insertion Sites
EcoRI
Gene Modification
RNA Editing
Modification Domain
Single base pair
Carrier Type
Lentivirus
Transformation Accuracy
0.97
Cell Culture
Adherent Culture
Target
DNMT3A
Alternative Names
DNMT3A; DNMT3A2; M.HsaIIIA; TBRS; DNA (cytosine-5-)-methyltransferase 3 alpha; DNA methyltransferase 3 alpha; HESJAS
Gene ID
Q9Y6K1(Human); O88508(Mouse); Q1LZ53(Rat)
UniProt ID
1788(Human); 13435(Mouse); 444984(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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