Anti-DR5 (clone AMG6Z5L5L) SynExpress C-mCh-I4-K Modified CD8+ T cells

CAT#: ITS-1224-CR2268
Clone: AMG6Z5L5L
Host: Human
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: CMV-mCherry-IL-4-KpnI
Carrier Type: pGEX
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target DR5 (clone AMG6Z5L5L). We employs the pGEX (CMV-mCherry-IL-4-KpnI) vector components and the SynExpress system of the Exons Knock-in/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
DR5
Clone
AMG6Z5L5L
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
CMV
Effector Gene
IL-4
Insertion Sites
KpnI
Gene Modification
Knock-in
Modification Domain
Exons
Carrier Type
pGEX
Transformation Accuracy
0.9
Cell Culture
Adherent Culture
Target
DR5
Alternative Names
TNFRSF10B; CD262; DR5; KILLER; KILLER/DR5; TRAIL-R2; TRAILR2; TRICK2; TRICK2A; TRICK2B; TRICKB; ZTNFR9; tumor necrosis factor receptor superfamily member 10b; TNF receptor superfamily member 10b
Gene ID
O14763(Human)
UniProt ID
8795(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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