Anti-DR6 (clone 4IB2E) SynExpress C-mKa-cJ-K Modified CD8+ T cells

CAT#: ITS-1224-CR2308
Clone: 4IB2E
Host: Mouse
Cell Source: Modified CD8+ T cells
Species Reactivity: Human
Connector Fragments: CMV-mKate-c-Jun-KpnI
Carrier Type: AAV
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target DR6 (clone 4IB2E). We employs the AAV (CMV-mKate-c-Jun-KpnI) vector components and the SynExpress system of the Single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
Mouse
Target
DR6
Clone
4IB2E
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mKate
Promoter
CMV
Effector Gene
c-Jun
Insertion Sites
KpnI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.87
Cell Culture
Suspension Culture
Target
DR6
Alternative Names
TNFRSF21; BM-018; CD358; DR6; tumor necrosis factor receptor superfamily member 21; TNF receptor superfamily member 21
Gene ID
O75509(Human)
UniProt ID
27242(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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