Creative Biolabs-Immuno-oncology

Anti-EphA2 (clone SPL2D) SynExpress E1-Cy3-NF-B CD4+ T Cells (CAT#: ITS-1124-CR403)

DatasheetDatasheet
Description
This product utilizes CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target EphA2 ( clone SPL2D). We employs the AAV (EF1α-Cy3-NF-κB-BamHI) vector components and the SynExpress system of the lncRNA Base Editing/Delayed feedback for a robust and sustained response against cancers.
Host
Mouse
Target
EphA2
Clone
SPL2D
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
Cy3
Promoter
EF1α
Effector Gene
NF-κB
Insertion Sites
BamHI
Gene Modification
Base Editing
Modification Domain
lncRNA
Carrier Type
AAV
Transformation Accuracy
0.98
Cell Culture
Suspension Culture
Case Studies
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