Anti-ERBB3 (clone 4C508F) SynExpress trc-mCh-TF-E NK Cells

CAT#: ITS-1124-CR424
Clone: 4C508F
Host: Humanized
Cell Source: NK cells
Species Reactivity: Human
Connector Fragments: trc-mCherry-TFIIA-EcoRI
Carrier Type: Lentivirus
Description
This product utilizes NK cells that have been engineered with our proprietary GeneCircuit technology to specifically target ERBB3 ( clone 4C508F). We employs the Lentivirus (trc-mCherry-TFIIA-EcoRI) vector components and the SynExpress system of the single base pair Knockout/Adaptive feedback for a robust and sustained response against cancers.
Host
Humanized
Target
ERBB3
Clone
4C508F
Species Reactivity
Human
Cell Source
NK cells
Sensor Gene
mCherry
Promoter
trc
Effector Gene
TFIIA
Insertion Sites
EcoRI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
Lentivirus
Transformation Accuracy
0.91
Cell Culture
3D Culture
Target
ERBB3
Alternative Names
ERBB3; ErbB-3; HER3; LCCS2; MDA-BF-1; c-erbB-3; c-erbB3; erbB3-S; p180-ErbB3; p45-sErbB3; p85-sErbB3; erb-b2 receptor tyrosine kinase 3; FERLK; VSCN1
Gene ID
P02771(Human); P02772(Mouse); P02773(Rat)
UniProt ID
2065(Human); 29496(Rat)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
Online Inquiry