This product utilizes Dendritic cells that have been engineered with our proprietary GeneCircuit technology to specifically target GITR (clone 36Zh5L). We employs the Lentivirus (EF1α-TurboGFP-c-Fos-XbaI) vector components and the SynExpress system of the Multiple base pair Insertion/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
GITR
Clone
36Zh5L
Species Reactivity
Human
Cell Source
Dendritic cells
Sensor Gene
TurboGFP
Promoter
EF1α
Effector Gene
c-Fos
Insertion Sites
XbaI
Gene Modification
Insertion
Modification Domain
Multiple base pair
Carrier Type
Lentivirus
Transformation Accuracy
0.9
Cell Culture
Suspension Culture
Target
GITR
Alternative Names
TNFRSF18; AITR; CD357; GITR; GITR-D; tumor necrosis factor receptor superfamily member 18; TNF receptor superfamily member 18; ENERGEN
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.