Creative Biolabs-Immuno-oncology

Anti-GITR (clone 3d6Z) SynExpress E1-G-L/T-E Synthetic CD4+ T cells (CAT#: ITS-1224-CR490)

DatasheetDatasheet
Description
This product utilizes Synthetic CD4+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GITR (clone 3d6Z). We employs the AAV (EF1α-GFP-LEF/TCF-EcoRI) vector components and the SynExpress system of the Exons Deletion/Delayed feedback for a robust and sustained response against cancers.
Host
Human
Target
GITR
Clone
3d6Z
Species Reactivity
Human
Cell Source
Synthetic CD4+ T cells
Sensor Gene
GFP
Promoter
EF1α
Effector Gene
LEF/TCF
Insertion Sites
EcoRI
Gene Modification
Deletion
Modification Domain
Exons
Carrier Type
AAV
Transformation Accuracy
0.88
Cell Culture
Suspension Culture
Case Studies
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