Creative Biolabs-Immuno-oncology

Anti-GITR (clone 4I8PA9Q) SynExpress pU-Cy3-I10-E Modified CD8+ T cells (CAT#: ITS-1224-CR478)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GITR (clone 4I8PA9Q). We employs the AAV (pUC-Cy3-IL-10-EcoRI) vector components and the SynExpress system of the Single base pair Knockout/Positive feedback for a robust and sustained response against cancers.
Host
Human
Target
GITR
Clone
4I8PA9Q
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
Cy3
Promoter
pUC
Effector Gene
IL-10
Insertion Sites
EcoRI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.95
Cell Culture
Suspension Culture
Case Studies
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