Creative Biolabs-Immuno-oncology

Anti-GITR (clone 4I8PH7J) SynExpress SV-mCh-NF-X Engineered Tregs (CAT#: ITS-1224-CR475)

DatasheetDatasheet
Description
This product utilizes Engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target GITR (clone 4I8PH7J). We employs the pAS (SV40-mCherry-NF-κB-XbaI) vector components and the SynExpress system of the Single base pair Base Editing/Delayed feedback for a robust and sustained response against cancers.
Host
Human
Target
GITR
Clone
4I8PH7J
Species Reactivity
Human
Cell Source
Engineered Tregs
Sensor Gene
mCherry
Promoter
SV40
Effector Gene
NF-κB
Insertion Sites
XbaI
Gene Modification
Base Editing
Modification Domain
Single base pair
Carrier Type
pAS
Transformation Accuracy
0.85
Cell Culture
3D Culture
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For Research Use Only | Not For Clinical Use

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