Creative Biolabs-Immuno-oncology

Anti-GITR (clone 4I9Qa1G) SynExpress pB-mCh-I10-B Modified CD8+ T cells (CAT#: ITS-1224-CR495)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GITR (clone 4I9Qa1G). We employs the AAV (pBAD-mCherry-IL-10-BamHI) vector components and the SynExpress system of the Histone modification sites RNA Editing/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
GITR
Clone
4I9Qa1G
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
pBAD
Effector Gene
IL-10
Insertion Sites
BamHI
Gene Modification
RNA Editing
Modification Domain
Histone modification sites
Carrier Type
AAV
Transformation Accuracy
0.99
Cell Culture
Suspension Culture
Case Studies
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