Creative Biolabs-Immuno-oncology

Anti-GITR (clone A2E7J) SynExpress E1-mCh-I10-H Modified CD8+ T cells (CAT#: ITS-1224-CR1043)

DatasheetDatasheet
Description
This product utilizes Modified CD8+ T cells that have been engineered with our proprietary GeneCircuit technology to specifically target GITR (clone A2E7J). We employs the AAV (EF1α-mCherry-IL-10-HindIII) vector components and the SynExpress system of the Single base pair Knockout/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
GITR
Clone
A2E7J
Species Reactivity
Human
Cell Source
Modified CD8+ T cells
Sensor Gene
mCherry
Promoter
EF1α
Effector Gene
IL-10
Insertion Sites
HindIII
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.95
Cell Culture
Suspension Culture
Case Studies
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