Anti-GPC3 (clone 6A16A) SynExpress pB-mCh-NF-B Engineered Tregs

CAT#: ITS-1124-CR268
Clone: 6A16A
Host: Human
Cell Source: Engineered Tregs
Species Reactivity: Human
Connector Fragments: pBAD-mCherry-NF-κB-BamHI
Carrier Type: Retrovirus
Description
This product utilizes engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target GPC3 ( clone 6A16A). We employs the Retrovirus (pBAD-mCherry-NF-κB-BamHI) vector components and the SynExpress system of the exons Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
GPC3
Clone
6A16A
Species Reactivity
Human
Cell Source
Engineered Tregs
Sensor Gene
mCherry
Promoter
pBAD
Effector Gene
NF-κB
Insertion Sites
BamHI
Gene Modification
Base Editing
Modification Domain
Exons
Carrier Type
Retrovirus
Transformation Accuracy
0.85
Cell Culture
3D Culture
Target
GPC3
Alternative Names
GPC3; DGSX; GTR2-2; MXR7; OCI-5; SDYS; SGB; SGBS; SGBS1; Glypican 3
Gene ID
P04083(Human); P10107(Mouse); P07153(Rat)
UniProt ID
2719(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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