Creative Biolabs-Immuno-oncology

Anti-GPC3 (clone 6A16A) SynExpress pB-mCh-NF-B Engineered Tregs (CAT#: ITS-1124-CR268)

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Description
This product utilizes engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target GPC3 ( clone 6A16A). We employs the Retrovirus (pBAD-mCherry-NF-κB-BamHI) vector components and the SynExpress system of the exons Base Editing/Negative feedback for a robust and sustained response against cancers.
Host
Human
Target
GPC3
Clone
6A16A
Species Reactivity
Human
Cell Source
Engineered Tregs
Sensor Gene
mCherry
Promoter
pBAD
Effector Gene
NF-κB
Insertion Sites
BamHI
Gene Modification
Base Editing
Modification Domain
Exons
Carrier Type
Retrovirus
Transformation Accuracy
0.85
Cell Culture
3D Culture
Case Studies
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