Creative Biolabs-Immuno-oncology

Anti-GPC3 (clone A1-042S) SynExpress C-mCh-cF-X Regulatory B Cells (CAT#: ITS-1124-CR280)

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Description
This product utilizes regulatory B cells that have been engineered with our proprietary GeneCircuit technology to specifically target GPC3 ( clone A1-042S). We employs the AAV (CMV-mCherry-c-Fos-XbaI) vector components and the SynExpress system of the single base pair Knockout/Balancing feedback for a robust and sustained response against cancers.
Host
Human
Target
GPC3
Clone
A1-042S
Species Reactivity
Human
Cell Source
Regulatory B cells
Sensor Gene
mCherry
Promoter
CMV
Effector Gene
c-Fos
Insertion Sites
XbaI
Gene Modification
Knockout
Modification Domain
Single base pair
Carrier Type
AAV
Transformation Accuracy
0.85
Cell Culture
3D Culture
Case Studies
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