Anti-GPC3 (clone M4B38D) SynExpress pL-Cy2-I17-B Engineered Tregs

CAT#: ITS-1124-CR258
Clone: M4B38D
Host: Human
Cell Source: Engineered Tregs
Species Reactivity: Human
Connector Fragments: pL-Cy2-IL-17-BamHI
Carrier Type: Lentivirus
Description
This product utilizes engineered Tregs that have been engineered with our proprietary GeneCircuit technology to specifically target GPC3 ( clone M4B38D). We employs the Lentivirus (pL-Cy2-IL-17-BamHI) vector components and the SynExpress system of the exons Knockout/Delayed feedback for a robust and sustained response against cancers.
Host
Human
Target
GPC3
Clone
M4B38D
Species Reactivity
Human
Cell Source
Engineered Tregs
Sensor Gene
Cy2
Promoter
pL
Effector Gene
IL-17
Insertion Sites
BamHI
Gene Modification
Knockout
Modification Domain
Exons
Carrier Type
Lentivirus
Transformation Accuracy
0.85
Cell Culture
Suspension Culture
Target
GPC3
Alternative Names
GPC3; DGSX; GTR2-2; MXR7; OCI-5; SDYS; SGB; SGBS; SGBS1; Glypican 3
Gene ID
P04083(Human); P10107(Mouse); P07153(Rat)
UniProt ID
2719(Human)
Format
Lyophilized/Liquid
Shipping
All cell products are transported using dry ice, or specialized refrigerated containers to ensure that their temperature remains within an appropriate range. For cell products that are particularly sensitive to temperature, transportation must be carried out in liquid nitrogen tanks to ensure the quality and viability of the products.
Handling Advice
Handle cells in a sterile environment to prevent contamination. Use aseptic techniques when transferring to new media or containers. Follow biosafety regulations for disposing of cell waste.
Storage
Keep cell products in the designated temperature range (usually liquid nitrogen or -80°C) to maintain viability.
For Research Use Only | Not For Clinical Use
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